Bailey regained her confidence with Custom Rx Treatment.

After years of relentless acne breakouts, dark spots, dermatologist appointments, and prescriptions that didn’t work, Bailey found clearer skin with Ro Derm.

After years of relentless acne breakouts, dark spots, dermatologist appointments, and prescriptions that didn’t work, Bailey found clearer skin with Ro Derm.
BailyAcneDark Spots

“I’ve been receiving compliments on how great my skin looks...My skin hasn’t been this clear or looked this great in years. This is the longest I’ve gone without one breakout, too! I feel so much better and I’ve had a major confidence boost.”

Ro Derm memberVerified
Start now Your Custom Rx Treatment formula may be different from Bailey's. Your healthcare provider will choose an appropriate formula for your skin and skin concerns. Bailey submitted her testimonial for Rory Nightly Defense, which is the previous name of Ro Derm Custom Rx Treatment—the formula did not change when the product was renamed. She received her treatment at no cost for offering her photos and testimonial.

Dermatologist-selected ingredients.

Ingredients matter when it comes to taking care of your skin. That’s why every treatment blend is personalized to help you achieve your skin goals. If prescribed, your Custom Rx Treatment may contain:

Tretinoin

Tretinoin

Targets:

Fine lines and wrinkles Dark spots Uneven skin tone and texture Acne Clogged pores Dull skin
Important Safety information
Azelaic acid

Azelaic acid

Targets:

Acne Blemishes Inflammation Uneven skin tone
Important Safety information
Niacinamide

Niacinamide

Offsets the appearance of:

Dark spots Dryness Dullness Uneven skin tone
Vitamin E

Vitamin E

Offsets the appearance of:

Dryness Uneven skin texture
Tranexamic acid

Tranexamic acid

Offsets the appearance of:

Dark spots Discoloration Uneven skin tone
Ceramides

Ceramides

Offsets the appearance of:

Dryness Uneven texture
Hyaluronic acid

Hyaluronic acid

Offsets the appearance of:

Dryness Flakiness

Introducing the full Custom Rx System.

Make your routine fuss-free with our dermatologist-designed skincare system (because we know you have other things to think about).

  • Custom Rx Treatment Your personalized prescription formula
  • Hydrating Cleanser The refreshing way to start your routine
  • Protecting SPF Lotion Broad spectrum SPF 28 sunscreen for everyday use

1 Take $20 off your 30-day trial

If you love it, we’ll keep the momentum going with bimonthly shipments:

  • Custom Rx Treatment - $29 $9/first month After your 30-day trial ends, you will automatically be shipped a new order every 2 months thereafter. You will be billed $58 for each order. Cancel any time in your My Ro account.
  • Custom Rx System - $41 $21/first month After your 30-day trial ends, you will automatically be shipped a new order every 2 months thereafter. You will be billed $82 for each order. Cancel any time in your My Ro account.

Your goals are our goals

And we love hearing about how things are going

“My skin has drastically changed. It's more clear, no new breakouts, visibly less scarring...my skin feels fresh!”

Ro Derm memberVerified

“Incredible. I have my skin back, along with my confidence!”

Ro Derm memberVerified

“I'm 49 and people say my skin looks 28.”

Ro Derm memberVerified

“I know tretinoin and niacinamide can take several months to notice results, but in the 3 months I’ve been using it I’ve noticed results. My pores are smaller and look less clogged. My skin texture is smoother.”

Ro Derm memberVerified

“I was amazed at how quickly I received my order and how helpful my doctor has been.”

Ro Derm memberVerified

“My skin has improved so much since using this product.”

Ro Derm memberVerified

“Trustworthy, convenient, personalized care!”

Ro Derm memberVerified

These testimonials were submitted by verified members for Rory Nightly Defense, which is the previous name of Ro Derm Custom Rx Treatment—the formulas did not change when the product was renamed. The members received their treatment at no cost for offering their photos and/or testimonials.

Woman holding Ro Derm skincare product.

Ongoing care with unlimited follow‑ups

From acne to fine lines and wrinkles, get personalized, prescription Custom Rx Treatment. Then, add on our cleanser and moisturizer to round out your skincare routine.

GETTING STARTED

How it works

Free visit

Free visit

Start with a free 10-minute online visit, designed by dermatologists, to share your specific skin concerns and goals. If appropriate, a US-licensed healthcare professional will then prescribe your personalized Custom Rx Treatment.

Free 2-day shipping

Because we know how excited you are to begin your treatment (and we’re excited for you, too).

Free and unlimited check-ins

Free and unlimited check-ins

You’re not on your skincare journey alone. Your provider will follow up on your progress, help you manage any side effects, and, as your skin evolves, adjust your treatment as needed to optimize results.

Questions?
Let us help.

What is Custom Rx Treatment?

Custom Rx Treatment is a customized skincare treatment that is intended to be used on the face. It is a compounded drug product, which means it is a mixture of different ingredients that are each selected based on your specific needs. While compounded medications are not FDA-approved, they serve an important patient need—especially when FDA-approved medication is not available for treatment.

Our team of experts, including dermatologists and our very own Chief Medical Officer, created the Custom Rx Treatment formulations and selected a cleanser and SPF lotion to complement them.

If prescribed, there are several different ingredients that may end up in your formulation of Custom Rx Treatment. Through Ro Derm, you’ll be connected with a US-licensed healthcare professional who will select the most appropriate combination of ingredients, tailoring the formulation to your specific skin concerns and goals. You will receive information about the ingredients in your formulation in your treatment plan."

What’s in the Custom Rx Treatment?

Custom Rx Treatment is made with a blend of ingredients that were hand-selected by a dermatologist and customized to fit your needs. Depending on your specific skin type, concerns, and goals, the ingredients in your Custom Rx Treatment may include:

Tretinoin
(see Important Safety Information)

Azelaic acid
(see Important Safety Information)

Niacinamide

Vitamin E acetate

Magnesium ascorbyl phosphate (MAP)

Tranexamic acid

Ceramides

Hyaluronic acid

If prescribed, you will receive a detailed treatment plan that describes which ingredients are included in your custom formulation.

Can I use Custom Rx Treatment with my other skincare products?

In many cases, yes. Depending on your specific treatment, your provider may recommend avoiding skincare products that have ingredients such as salicylic acid, glycolic acid, or benzoyl peroxide—at least during the beginning weeks of treatment. If you have any questions about specific products, you can message your provider for guidance. If you are using other topical prescription medications, make sure to tell your provider.

Prescription skincare can make your skin more prone to irritation and sensitive to the sun, so Ro Derm offers its own dermatologist-selected skincare products to complement your treatment: its refreshing Hydrating Cleanser and its UVA/UVB broad-spectrum sunscreen, Protecting SPF Lotion. For those engaging in extended outdoor activity, a stronger broad-spectrum sunscreen with an SPF of at least 30 is recommended.

When will I start to see improvement with my skin?

When using Custom Rx Treatment, the timing of the effects of your treatment will be dependent on many factors, including your specific skincare goals (e.g., reducing the appearance of fine lines and wrinkles, reducing redness, etc.), how severe your symptoms are, how well you tolerate the treatment, and others. It is also important to understand that—for certain treatments—your skin may appear worse before it gets better. Depending on the treatment you are prescribed, you will receive detailed information on the formulation, what to expect and when, as well as tips on how to mitigate any side effects such as redness, peeling, and flaking that may occur as your skin acclimates to the treatment.

Have another question?
You might find the answer on our FAQ page. If not, give us a call at (424) 347-6299 or email us at care@ro.co.